Phenylboric acid derivatives have a wide variety and rapid development. In recent years, they have been widely used in electronic, chemical, pharmaceutical, biological and other fields, such as liquid crystal display materials, chemiluminescence enhancers, wood preservatives and enzyme inhibitors. In addition, they can selectively promote the transport of glucose through the lipid bilayer. At present, they are increasingly used as molecular recognition units, especially, It is used to design and synthesize boron exogenous lectin (glycoprotein) and carbohydrate sensor.
    Characteristics of phenylboric acid and its derivatives
    Phenylboronic acid derivatives have two forms in aqueous solution: charged and uncharged. Only the charged form can form reversible five-membered or six-membered cyclic esters with polyhydroxy compounds with 1,2 - or 1,3-diol groups. This process is reversible, and there are a large number of such polyhydroxy compounds in nature, such as polysaccharides, many of which exist in organisms and have an important impact on biological activities.